NICOLE LAZARUS

Pioneered the development of novel mouse models for anemia and lung injury, significantly reducing experimental variability by 25%.

Designed and executed over 10 critical PK/PD studies, directly informing lead candidate selection for IND submission.

Optimized 25-30-color spectral cytometry panels across 3 distinct programs, accelerating high-throughput biomarker discovery.

Conducted comprehensive RNAseq analysis, identifying over 5 novel immune gene signatures currently under clinical evaluation.

Mentored 3 junior scientists and provided comprehensive training on cytometry data analysis workflows to cross-functional teams.

Directed and optimized multi-parameter flow cytometry and cell sorting operations for a translational immunology lab, enhancing research throughput.

Developed and validated over 25 high-parameter cytometry panels, directly supporting clinical and animal studies in SIV/HIV, TB, and lung injury.

Served as interim FACS core director from 2020-2021, successfully supervising core operations and comprehensive user training.

Co-authored over 10 peer-reviewed publications in immunology and infectious disease journals, disseminating key research findings.

Led laboratory safety compliance initiatives and optimized reagent procurement, improving operational efficiency and resource management.

Managed comprehensive in vivo pharmacology and flow cytometry studies for preclinical fibrosis and colitis models, advancing disease understanding.

Designed and executed analysis of complex cytokine response profiles utilizing ELISpot, Luminex, and FlowJo platforms, providing critical insights.

Mentored undergraduate researchers, fostering scientific development and contributing to multiple peer-reviewed publications.